Our new Very clear+ tissue clearing procedure is the one technique that delipidates samples without adjust in morphology and with negligible effect on structural integrity.
Megatome is usually a vibrating microtome made to portion a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome permits large-throughput tissue sectioning with uniform area profile, in addition to minimum tissue injury and data reduction.
Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a unique deflection control mechanism.
SE works by using a rotational electric powered area to disperse really electromobile molecules (including antibodies or surfactant micelles) in the course of a porous sample without harmful electrically charged buildings throughout the tissue. This permits 2-4 day clearing of intact organs,
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eFLASH is actually a rapid tissue labeling procedure that permits for uniform full-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed all over intact tissue volumes, although its modular structure lets you upgrade and personalize individual parts.
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Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, shielding specimens for various rounds of processing.
Leverage the Crystal clear+ tissue clearing process, as well as eFLASH and patented stochastic electrotransport systems, to swiftly apparent and label complete organs. Crucial highlights and features consist of:
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